SpineThera, Inc. to collaborate with Mayo Clinic to advance solutions in substance abuse disorder treatment

June 17, 2024

SpineThera, Inc. to collaborate with Mayo Clinic to advance solutions in substance abuse disorder treatment

[Plymouth, MN] June 17, 2024 – SpineThera, Inc., apharmaceutical company specializing in long-acting injectable technology, hasannounced it has entered into a know-how agreement with Mayo Clinic. Thiscollaboration aims to develop long-acting injectable drugs to improve treatmentoutcomes for individuals with substance abuse disorders.

The opioid epidemic remains asignificant public health crisis, impacting millions worldwide. There is a need to develop treatmentoptions that improve outcomes, increase patient access to supervised treatment,and reduce risk associated with existing treatments.

The project will be led by SpineThera CEO, Jeff Missling,and Chair for Addiction Medicine at Mayo Clinic, Tyler Oesterle, M.D.  

 

Misslingcommented on the significance of the collaboration, “SpineThera’s novel,long-acting injectable technology has potential in multiple therapeutic areas.We are honored to move strategically into substance abuse disorder treatmentthrough this collaboration. Despite multiple approved medications for thetreatment of opioid use disorder, we are still losing too many people to thiscrisis every day and seek to make a difference through our contributions."

By leveraging SpineThera’s long-acting injectabletechnology and Mayo Clinic’s expertise in addiction medicine, thiscollaboration seeks to develop more effective and accessible treatment options.SpineThera is committed to addressing this healthcare challenge and improvingthe lives of individuals affected by substance abuse disorders. 

Mayo Clinic has a financialinterest in the technology referenced in this press release. Mayo Clinic willuse any revenue it receives to support its not-for-profit mission in patientcare, education and research.

 

AboutSpineThera, Inc.:

SpineThera is aclinical stage pharmaceutical company working to improve the lives of patientsby creating long-acting injectable drugs utilizing its patentedmicro-suspension platform technology. SpineThera’s micro-suspension providesmonths long sustained release of the active pharmaceutical ingredient withsuperior injectability at ultra-high concentrations. Our goal is to developproprietary drugs that offer patients and physicians new treatment options thatreduce risk, improve outcomes, and manage overall treatment costs in marketswith few or no approved drugs.

SpineThera'sflagship investigational drug product, SX600, is a dexamethasone acetatemicro-suspension injection which has been engineered as a targeted,extended-release corticosteroid with the potential to demonstrate asubstantially improved benefit-risk profile compared to current epiduralsteroid injections for radicular leg pain. SpineThera, Inc., is based inMedical Alley, Minnesota, the global epicenter of health innovation and care.For more information visit: www.spinethera.com.

For media inquiries or further information, please contact:

Jeff Missling,CEO

jmissling@spinethera.com

612-508-4795

August 22, 2019

SpineThera receives u.s. patent covering sustained-release injectable corticosteroid, sx600, a non-opioid drug in development for low back pain

SpineThera’s clinical development program for SX600 will evaluate sustained-release, injectable treatment options for pain in and near the spine Minneapolis, MN – August 22, 2019 - SpineThera, Inc., a privately held, clinical stage pharmaceutical company, announced today that the United States Patent and Trademark Office has issued Patent 10,350,222 related to its non-opioid, sustained-release drug technology.
October 22, 2018

Purdue Pharma L.P. Enters into Exclusive Option Agreement to Acquire SpineThera, Inc. and Its Non-Opioid Product in Development for Epidural Steroid Injection for the Treatment of Low Back Pain

Purdue will support SpineThera’s clinical development program to evaluate sustained-release, injectable treatment options for pain in and near the spine October 22, 2018 03:07 PM Eastern Daylight Time. STAMFORD, Conn. & PLYMOUTH, Minn.--(BUSINESS WIRE)--Purdue Pharma L.P. and SpineThera, Inc. today announced that the companies have entered into an agreement that provides Purdue the exclusive option to acquire SpineThera, Inc. and gain worldwide rights to its products and technology platforms, including lead asset SX600, a novel dexamethasone containing microsphere that is in development for epidural administration for low back pain. This technology has potential for development of non-opioid treatments for acute and chronic pain.
October 10, 2017

SpineThera to Present at Discovery Square Innovators & Investors Forum

On October 10, 2017 the Mayo Clinic Center for Individualized Medicine, Destination Medical Center, and Medical Alley Association are hosting the Discovery Square Innovators + Investors Forum at the Mayo Civic Center.

Proven health impact

SpineThera produce more effective health-benefit leads, with a higher hit rate, in less time than any other method available today.